Alexander J Andre Cobb
University of Reading, UK
Title: New asymmetric organocatalytic methods towards the synthesis of molecules of biological interest
Biography
Biography: Alexander J Andre Cobb
Abstract
The use of asymmetric organocatalysis as a method towards the construction of enantiopure molecules has burgeoned significantly in the last decade or so. Our group has developed several new reactions that lead to highly enantiopure biomolecules – mainly non-natural amino acids – using hydrogen bonding catalysis. We present the expedient synthesis of novel g- and d-amino acids, as well as other novel complex structures and derivatives, such as an analogue of the Amaryllidaceae alkaloid a-lycorane.