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Vladislav Yu. Korotaev

Vladislav Yu. Korotaev

Ural Federal University, Russia

Title: 3-Nitro-2-(trihalomethyl)-2H-chromenes in Reactions with 1,3-Dipoles: Synthesis and Cytotoxic Activity of 3-Annulated Chromane Derivatives

Biography

Biography: Vladislav Yu. Korotaev

Abstract

The [3+2] cycloaddition of sodium azide and stabilized azomethine ylides to 3-nitro-2-(trihalomethyl)-2H-chromenes 1 and 2 was studied and cycloadducts 3‒8 were synthesized. The cytotoxic activity of D3-annulated chromane derivatives is discussed.