Pharmaceutical Chemistry

Biography

Sandrine Ongeri has completed her PhD in 1999 from Université Paris Descartes (France) and postdoctoral studies from the University of Milano (Italy). During her PhD, she spent one year at Oxford University (UK). She is group currently leader at the University Paris Sud. Her group focuses on the design, the synthesis and biophysical evaluations of peptidomimetics as inhibitors of protein-protein interactions involving beta-sheet structures, in particular in amyloid proteins aggregation. Her group's research  is also expert in the synthesis of unantural fluorinated amino acids and in the use of fluorine as probe in peptide-protein interaction.

Abstract

Abstract : Designed peptidomimetics disrupt protein-protein interactions mediating amyloid protein aggregation